Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Giants | at |  | Pirates | 6:40pm ET | Verlander R (1-8) | Falter L (7-5) | 6:40pm |
 | Twins | at |  | Tigers | 6:40pm ET | Paddack R (3-9) | Mize R (9-4) | 6:40pm |
 | Astros | at |  | Marlins | 6:40pm ET | - | Alcantara R (5-9) | 6:40pm |
 | Orioles | at |  | Phillies | 6:45pm ET | Morton R (6-8) | Luzardo L (8-5) | 6:45pm |
 | Guardians | at |  | Mets | 7:10pm ET | Cecconi R (5-4) | Manaea L (1-1) | 7:10pm |
 | Royals | at |  | Red Sox | 7:10pm ET | Hill L (0-2) | Giolito R (6-2) | 7:10pm |
 | Brewers | at |  | Braves | 7:15pm ET | Priester R (9-2) | - | 7:15pm |
 | Yankees | at |  | Rangers | 8:05pm ET | Warren R (6-5) | Eovaldi R (8-3) | 8:05pm |
 | Reds | at |  | Cubs | 8:05pm ET | Lodolo L (8-6) | Rea R (8-4) | 8:05pm |
 | Blue Jays | at |  | Rockies | 8:40pm ET | Lauer L (6-2) | Gordon L (2-2) | 8:40pm |
 | Rays | at |  | Angels | 9:38pm ET | Littell R (8-8) | Kikuchi L (4-7) | 9:38pm |
 | Padres | at |  | Diamondbacks | 9:40pm ET | Darvish R (0-3) | Pfaadt R (10-6) | 9:40pm |
 | Cardinals | at |  | Dodgers | 10:10pm ET | Gray R (10-4) | Yamamoto R (9-7) | 10:10pm |
