The Baltimore Orioles placed right-hander Grayson Rodriguez on the 15-day injured list Wednesday with shoulder inflammation.

Rodriguez, 24, is off to a strong start to his second season. He is 4-1 with a 3.71 ERA through six starts, striking out 37 batters in 34 innings. He pitched 5 2/3 shutout innings in Monday's 2-0 win against the New York Yankees.

Baltimore's 2018 first-round pick (11th overall) is 11-5 with a 4.21 ERA in 29 games (all starts) since making his MLB debut on April 5, 2023.

The Orioles activated left-hander John Means from the 15-day IL in a corresponding transaction. He has not pitched in the majors this season while dealing with a left forearm strain.

Means is 1-2 with an 8.68 ERA in six starts this season at Triple-A Norfolk.

Means, 31, was an All-Star in 2019 and owns a 21-26 record with a 3.74 ERA in 74 games (69 starts) since debuting with Baltimore in 2018.