San Diego Padres star third baseman Manny Machado departed Wednesday night's game against the host Los Angeles Angels in the fourth inning with an apparent leg injury.

Machado reached on a fielder's choice when he hit a grounder to third and Fernando Tatis Jr. was forced out at second. As he approached first, Machado seemed to feel something and after running through the bag, he stopped in short right field and leaned down from the waist.

Padres manager Mike Shildt and a trainer had lengthy discussions with Machado, who eventually walked toward first base. Shildt said a few more words to Machado, who suddenly veered to his left and walked to the Padres' dugout.

Donovan Solano pinch-ran for Machado and remained in the game at third base.

Machado was 0-for-2 on Wednesday to drop his average to .249. He has six homers and 32 RBIs in 60 games this season.