Los Angeles Rams head coach Sean McVay said that tight end Tyler Higbee (ankle) will go on Injured Reserve, according to Adam Grosbard of the Los Angeles Daily News. Higbee will be forced to miss at least the next four games. The earliest he'll be available to return for the Rams will be for their Week 16 matchup against the division-rival Seattle Seahawks. The 32-year-old wasn't really moving the fantasy needle much before his ankle injury, catching 20 of his 30 targets for 190 yards and two touchdowns for L.A. in nine games played (seven starts). With Higbee now out of the picture for the foreseeable future, all three of Colby Parkinson, Terrance Ferguson, and Davis Allen could see more targets, with Ferguson being the most attractive flier for fantasy managers in TE-premium leagues.

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Jacksonville Jaguars rookie running back Bhayshul Tuten (ankle) was listed as a limited practice participant on Wednesday due to an ankle injury that he suffered late in the Week 11 win over the Los Angeles Chargers on Sunday, according to ESPN's Adam Schefter. Backfield mate Travis Etienne Jr. (shoulder) was also injured on Sunday, which likely played a part in Tuten's career day. The 23-year-old had season-highs across the board in snap percentage (32%), rushing attempts (15), and rushing yards (74) while scoring his third touchdown of the year. Etienne and Tuten appear to be trending toward both playing this Sunday against the Arizona Cardinals, but Tuten's impressive performance against the Bolts might have earned him a bigger share of the backfield pie going forward. Tuten is only rostered in 37% of Yahoo leagues, so he's widely available and is worth a pickup with another good matchup on tap.

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Jacksonville Jaguars running back Travis Etienne Jr. (shoulder) is on the Week 12 injury report and was limited in Wednesday's practice with a shoulder injury. Both Etienne and Bhayshul Tuten (ankle) are a little banged up coming out of Sunday's blowout win over the Los Angeles Chargers, but the fact that they were both able to practice on Wednesday is a good sign that they will be available this weekend on the road in Las Vegas against the Raiders. Tuten played a season-high 32% of the offensive snaps in Week 11 and carried the ball a season-high 15 times for 74 yards and a touchdown, but that may have had something to do with Etienne's shoulder injury. Etienne played a season-low 49% of snaps but still saw 19 carries for 73 yards and two touchdowns in a run-heavy game script. The two backs could have more of an even split in another plus matchup in Week 12 against the Raiders if they are active.

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New Orleans Saints running back Alvin Kamara (ankle) is still dealing with an ankle issue coming out of the team's bye and was listed as a limited practice participant on Wednesday, according to Katherine Terrell of ESPN. Kamara has been a mainstay on the team's injury report ever since injuring his ankle in early October, but he hasn't missed any games. The 30-year-old's status bears watching heading into a Week 12 game this Sunday against the division-rival Atlanta Falcons, but he should be able to suit up. Negative game script certainly hasn't helped Kamara's cause in 2025, as he's averaging a career-low 3.6 yards per tote on 128 rushing attempts for 460 yards and just one touchdown in 10 games. The five-time Pro Bowler did have a season-high 22 carries for 83 yards on the ground in the Week 10 win over the Panthers, though. In a bad Saints offense, Kamara has become more of a high-end RB3/flex play.

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Baltimore Ravens tight end Isaiah Likely (calf) was held out of Wednesday's practice with a calf issue, according to Jamison Hensley of ESPN. Likely is dealing with a calf injury as the team prepares to face the New York Jets in Week 12 this Sunday, and the 25-year-old is now up in the air to play unless he can return to practice on Thursday or Friday. Likely missed some time early this year due to injury and just has not been able to get on a roll so far in 2025. He caught just two passes on three targets for 15 yards in last week's win over the Cleveland Browns and has only 12 receptions for 118 yards and no touchdowns on 16 targets in seven games played. Receiver Rashod Bateman (ankle) still isn't practicing and could miss another game as well. If Likely is out or limited this weekend, fellow TE Mark Andrews would be firmly in play as a TE1 in fantasy football.

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Houston Texans running back Nick Chubb has played a reduced role in the last few weeks, and it's hard to trust him this Thursday night, even in a favorable matchup against the Bills. Chubb played only 18 snaps (26%) in Week 11 against the Titans and had just three carries for 17 yards. It was his lowest number of carries in any game this season, and his third time in the last five weeks with five carries or fewer. The Bills allow the second-most fantasy points per game to running backs in the NFL, but it will likely be Woody Marks that gets most of the work in Week 12. Chubb has dropped to RB42 in RotoBaller's rankings and is not much more than an injury handcuff for Marks at this point in the season.

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Chicago Bears rookie wide receiver Luther Burden III has earned a bigger role on offense going forward, according to head coach Ben Johnson. "You get what you earn. And I think he's earned the increased snaps," Johnson said. Burden only played 44% of the offensive snaps in the Week 11 win over the Minnesota Vikings, but it was only the second time all year he has played over 40% of the snaps, and they have come in back-to-back weeks. The 21-year-old pass-catcher caught three of his five targets against Minnesota for 27 yards. The second-rounder out of Missouri has six grabs on eight targets the last two weeks for 78 yards. Burden has been inconsistent in his first year in the NFL in an offense with plenty of mouths to feed, but it sounds as though he'll have a chance to jump DJ Moore for the WR2 in Chicago before the year is over. Fantasy managers looking for WR depth could do worse than Burden. He's rostered in only 9% of Yahoo leagues.

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New England Patriots rookie running back TreVeyon Henderson has played well in Rhamondre Stevenson's (toe) absence the last three games, averaging 5.6 yards per carry for 264 yards and four touchdowns on 47 rushing attempts. Henderson also caught 10 passes for 66 yards and another touchdown. However, head coach Mike Vrabel was non-committal when asked if there will be a more even workload between the two once Stevenson is back from his injury, according to Tom Carroll of WEEI. "I think we'll probably have to have that conversation when it's certain that we're gonna have Rhamondre. He's gonna work through practice today, and we'll see where things go. TreVeyon's helped us, Rhamondre's helped us, Terrell [Jennings'] helped us." Stevenson returned to a limited practice on Wednesday, but it's unclear if he'll play in Week 12 against the Bengals. Fantasy managers who have Henderson are surely hoping that the impressive rookie has done enough recently to warrant a bigger workload when Stevenson is back.

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Houston Texans running back Woody Marks seems to be grabbing most of the work in his team's backfield, and he'll be a good flex option on Thursday Night Football against the Bills. Buffalo has allowed the second-most fantasy points per game to running backs, and the Bucs' Sean Tucker lit the Bills up for three touchdowns last week in Buffalo. In his team's Week 11 win over the Titans, Marks failed to find the end zone but had 18 carries for 44 yards and a seven-yard reception, while playing 66% of snaps. Nick Chubb only had three carries and played 26% of snaps, so Marks seems to be gaining more playing time in the timeshare coming down the stretch. Marks has double-digit carries in each of the five games since Houston's bye week, and the rookie checks in at No. 20 in this week's RotoBaller RB rankings. He's a fringe RB2 and an elite flex option for this matchup on Thursday Night Football.

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Detroit Lions head coach Dan Campbell said he'd "always" like to get running back David Montgomery more carries, according to Eric Woodyard of ESPN. Montgomery does have double-digit rushing attempts in seven of 10 games this year, including in three of the last four games. But he was more of an afterthought in Sunday night's 16-9 loss to the Philadelphia Eagles, carrying the ball only six times for 27 yards and catching his only target for 10 yards. The game script in Week 11 was not in the 28-year-old's favor, that's for sure. Detroit should have a better game script this weekend on the road against the one-win Tennessee Titans, so fantasy managers will be banking on him getting more involved on the ground again. Backfield mate Jahmyr Gibbs is much more dynamic than Montgomery in both the run and pass game, which has made Monty more of a touchdown-dependent RB3/flex in fantasy in 2025.

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Tennessee Titans rookie wide receiver Chimere Dike (chest) was listed as a full participant in Wednesday's practice despite leaving the Week 11 loss to the Houston Texans early with a chest injury. Dike should be fine to play in Week 12 versus the visiting Seattle Seahawks in a game in which the Titans are probably going to have to throw often. Meanwhile, fellow rookie Elic Ayomanor (hamstring) didn't practice on Wednesday after getting hurt on Sunday, and Calvin Ridley (leg) is done for the season after breaking his leg. The 23-year-old Dike could be in line for a heavy target load this weekend against Seattle, which would make him an attractive flex consideration in fantasy football. The fourth-rounder has caught only three passes for 19 yards in the last two games, but he did have 11 catches on 12 targets for 163 yards and a touchdown in Weeks 7 and 8 combined.

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Houston Texans quarterback Davis Mills will make his third straight start for the Texans after helping his team past the Jaguars and Titans the last two weeks. He'll face the Bills on Thursday night, stepping in for C.J. Stroud (concussion), who is still not ready to return. Mills has put up solid numbers in both his wins, throwing for 292 passing yards against the Jaguars and 274 passing yards against the Titans. He has three passing touchdowns and a rushing score in those two contests, while attempting over 40 pass attempts in each game. He can be a fringe start in two-QB leagues or even a bye-week fill-in for deep leagues, but he does have a tough home matchup against the Bills, who have allowed the fifth-fewest fantasy points to quarterbacks this season. If Mills has to try and keep up with Josh Allen, he could be poised for another high-volume game, but his tough matchup keeps him as the QB22 in RotoBaller's rankings for Week 12, meaning he isn't a great option in standard, single-QB leagues.

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Cincinnati Bengals running back Samaje Perine (ankle) is doubtful to play on Sunday against the New England Patriots as he continues to battle through a sprained ankle, according to Ben Baby of ESPN. Perine suffered a high-ankle sprain in the Week 9 loss to the Chicago Bears and was unable coming out of the bye to face the Pittsburgh Steelers in Week 11. The 30-year-old veteran is on track to miss a second straight game. It remains to be seen if Perine will be able to return for a big Week 13 divisional matchup against the Baltimore Ravens on Thanksgiving Day, but on a short week, it might be unlikely. With Perine out in last Sunday's loss to the Steelers, Tahj Brooks played only seven offensive snaps behind starter Chase Brown, carrying the ball once for a gain of five yards. Brown should see the vast majority of backfield work again this weekend against the Pats.

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Seattle Seahawks head coach Mike Macdonald said that running back Kenneth Walker is "earning more opportunities," but it is tied primarily to how Walker is performing during games, according to Michael-Shawn Dugar of The Athletic. Macdonald continues saying that Walker is doing well in practice, but the game context is what drives the decision-making. Walker's usage has been frustrating this season from a fantasy perspective as he has been stuck in an even time split with Zach Charbonnet, but his strong performance in Week 11 against the Rams could earn him more opportunities going forward. The 25-year-old totaled 16 carries for 67 yards and a touchdown to go along with three catches (three targets) for 44 yards in the game. Walker's impact in the pass game was something that Macdonald talked about as well, and with his game-changing explosiveness, Seattle could start to feature him as a bigger piece of the offense.

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Chicago Bears running back D'Andre Swift (hip) was listed as a limited participant in Wednesday's practice session, according to the team's official website. Swift has been a regular on the injury report with various nagging injuries and missed Chicago's Week 9 win over the Bengals, but has played in each of the past two weeks and resumed his lead-back role. The 26-year-old handled a season-high 21 carries for 90 yards in a Week 11 win over Minnesota. Rookie Kyle Monangai stayed involved with 13 touches for 37 yards and a rushing touchdown, but Swift has still been their best option. Swift was limited in Wednesday's practice last week before being upgraded to full on Thursday and Friday, and he should be on track to play again in Week 12 against the Pittsburgh Steelers.

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Kansas City Chiefs wide receiver Xavier Worthy (ankle) didn't participate in practice on Wednesday, according to the team's official website. Worthy tweaked his ankle during the Chiefs' Week 11 loss at the Denver Broncos, and his absence on Wednesday signals some doubt for his chances to suit up in Week 12 against the Indianapolis Colts. The 22-year-old wideout has dealt with multiple injuries this season, including a dislocated shoulder back in the season opener against the Chargers that caused him to miss two games. Worthy has had a disappointing stretch of games for fantasy managers since Rashee Rice returned in Week 7, recording 14 catches for 136 yards and no touchdowns on 23 targets across those four games. He'll have two more chances to practice this week to determine his status for a big Week 12 matchup against the Colts.

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Cincinnati Bengals quarterback Joe Burrow (toe) was listed as a full participant in Wednesday's practice, ESPN's Adam Schefter reports. Burrow was limited in practice every day last week, but he's made great progress in his recovery from the turf toe injury suffered in Week 2 against the Jacksonville Jaguars. The 28-year-old participated in 11-on-11 drills during Wednesday's practice, and there is a possibility that he will be able to make his return to the field on Sunday against the New England Patriots. Backup quarterback Joe Flacco was listed as limited in practice on Wednesday as he manages a shoulder injury, but he is expected to be ready to go this weekend versus the Patriots if the Bengals hold Burrow out for another week. The star quarterback said that he planned to return on Thanksgiving night against the Ravens, but the door is open for him to return in Week 12. Burrow should be immediately added if he is still available on the waiver wire in your leagues.

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Tennessee Titans rookie Elic Ayomanor (hamstring) is not participating in Wednesday's practice session, according to Paul Kuharsky of PaulKuharsky.com. Kuharsky reports that it may be difficult for Ayomanor to play on Sunday against the Seahawks due to the hamstring injury suffered during the Titans' loss to the Texans in Week 11. The rookie fourth-rounder caught only two of his six targets for 11 yards in the game. Ayomanor would have a great opportunity to emerge as the Titans' top wideout with Calvin Ridley (leg) out for the season, but his status will need to be monitored as the week goes along. If he is unable to play, fellow rookie Chimere Dike and Van Jefferson should see more opportunities, but neither can be trusted in fantasy lineups.

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Giana Han of The Baltimore Banner reports that Baltimore Ravens wide receiver Rashod Bateman (ankle) is not practicing with the team on Wednesday. Bateman sprained his ankle in the Week 10 win over the Minnesota Vikings and hasn't practiced or played since. Unless the 25-year-old can get back on the practice field on Thursday or Friday, he'll miss a second straight game this weekend against the New York Jets. After a career year in 2024 in which he had 756 receiving yards and nine touchdowns in 17 regular-season games, Bateman has become untrustworthy again for fantasy managers, as he currently has a 16-194-2 line on 31 targets through nine games. If he misses a second straight game, there will be more targets to go around for Zay Flowers and DeAndre Hopkins, and tight ends Mark Andrews and Isaiah Likely.

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New England Patriots wide receiver Kayshon Boutte (hamstring) is back at practice on Wednesday, according to Evan Lazar of Patriots.com. Boutte has missed the last two games due to a hamstring injury, but he was limited Monday through Wednesday of last week before being ruled out for the Thursday night win over the New York Jets in Week 11. In Weeks 6-8, the 23-year-old pass-catcher caught 10 of his 12 targets for 223 yards and four touchdowns, so fantasy managers shouldn't forget about the third-year wideout in an ascending Patriots offense. With Boutte out for the last two games, Mack Hollins and rookie Kyle Williams have had bigger roles in the passing attack. If Boutte can upgrade to a full practice this week, he stands a good chance of returning to a great matchup against a weak Cincinnati Bengals defense.

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