Buffalo Bills wide receiver Joshua Palmer (ankle, knee) is officially inactive for a divisional clash on Sunday against the Miami Dolphins in Week 10. Palmer put in limited practices this week, but the Bills didn't think he was ready to return to action just yet. The 26-year-old pass-catcher has not played since Week 6 and has been a disappointment so far in his first year in Buffalo after joining the team in free agency. With Palmer out again in Miami this weekend, the Bills will continue on with Khalil Shakir and Keon Coleman as their top options at the position, with Elijah Moore, Curtis Samuel, and Tyrell Shavers battling for WR3 targets. Palmer's next chance to return will be for a Week 11 tilt against the Tampa Bay Buccaneers. He should remain on the waiver wire in most fantasy leagues. Palmer has only 14 catches for 234 yards and no touchdowns so far in 2025 on 20 targets.

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Chicago Bears running back D'Andre Swift (groin, personal) is active for Sunday's Week 10 contest against the New York Giants. He had been listed as questionable after missing Friday's practice. The veteran ball-carrier has impressed when healthy this season, but after a short absence, he suddenly faces competition from standout rookie Kyle Monangai. With a wintry mix falling and a matchup against the Giants' 31st-ranked run defense, the Bears are expected to use a healthy dose of both Swift and Monangai out of the backfield on Sunday. Both can be low-end RB2 options in fantasy football.

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Cleveland Browns wide receiver Cedric Tillman (hamstring) has been activated from Injured Reserve and is officially active for the Week 10 contest on Sunday against the hosting New York Jets at MetLife Stadium. Tillman will be playing in his first game since injuring his hamstring in Week 4, so he could have some limitations in terms of his snap count this weekend. The matchup is a good one against a Jets secondary that just traded away All-Pro cornerback Sauce Gardner, but the 25-year-old will still be a pretty risky WR4/flex for fantasy managers in his first game back with rookie quarterback Dillon Gabriel now running the Browns' offense. Still, Tillman is worth a pickup off the waiver wire if he's available in your league and you need WR depth. Rookie wideout Isaiah Bond (foot) is out on Sunday, so it's possible Tillman is heavily involved right away.

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Cleveland Browns rookie linebacker Carson Schwesinger (ankle), who was listed as questionable for the Week 10 game against the New York Jets, is officially active on Sunday at MetLife Stadium. Schwesinger will be active despite suffering a high-ankle sprain in the team's Week 8 loss to the New England Patriots, but he was able to heal up during last week's bye. The 22-year-old could be slowed down a bit, but he was fortunate to suffer just a low-grade high-ankle sprain. He's been a bright spot for a capable Browns defense in his first year in the NFL, totaling 64 tackles (25 solo), a sack, four tackles for loss, one interception, and a pass breakup in his eight starts. The Browns' defense/special teams is a top-five fantasy option this weekend against a Jets team coming into the weekend with just one win on the season.

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The Jacksonville Jaguars have declared TE Hunter Long, RB Cody Schrader, DL Austin X. Johnson, WR Brian Thomas Jr., OL Ezra Cleveland and CB Jourdan Lewis inactive for Week 10.

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New Orleans Saints RB Alvin Kamara (ankle) is active for Week 10's game versus the Carolina Panthers.

Fantasy Spin: Kamara had been listed as questionable on the injury report after being a limited participant in all three of New Orleans' practice sessions during the week. He continues to be an important part of the Saints' running and passing games and can be viewed as a flex option or better in fantasy leagues.

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The Tampa Bay Buccaneers have declared DT CJ Brewer, LB Haason Reddick, OT Luke Haggard, LB Markees Watts, RB Bucky Irving, OG Elijah Klein and WR Chris Godwin inactive for Week 10.

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The New York Giants have declared C John Michael Schmitz, OG Evan Neal, PK Graham Gano, QB Jameis Winston, DE Victor Dimukeje, CB Paulson Adebo and DE Chauncey Golston inactive for Week 10.

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New York Jets wide receivers Allen Lazard and Adonai Mitchell are both healthy inactives for the team's Week 10 contest on Sunday against the Cleveland Browns. Despite Josh Reynolds (hip) being on Injured Reserve, Lazard will sit out coming out of the team's bye week. The 29-year-old caught just one of his two targets for five yards in the Week 8 win over the Cincinnati Bengals, and he has only seven catches for 45 yards and a touchdown in 2025 with the Jets. Mitchell was acquired from the Indianapolis Colts at Tuesday's trade deadline in the deal that sent All-Pro cornerback Sauce Gardner to the Colts, but the Jets don't think he's ready to contribute on offense just yet. John Metchie III, who was acquired from the Philadelphia Eagles last week, is active, though, and could be battling for WR2 duties behind Wilson in his debut with the team.

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Minnesota Vikings running back Aaron Jones Sr.(shoulder, toe) is officially active for Sunday's Week 10 contest against the Baltimore Ravens. He had been listed as questionable after logging a limited practice on Friday. Jones exited last week's game with a shoulder injury, but it wasn't too serious, and now he'll return to action just seven days later. The 30-year-old should lead the Vikings' backfield on Sunday, looking to build off his average of 8.7 yards per carry from Week 9. He remains a low-end RB2 in fantasy football.

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Cleveland Browns rookie tight end Harold Fannin Jr. (hamstring) is officially active on Sunday as the team takes on the New York Jets in Week 10. Fannin was added to this week's injury report after not practicing on Thursday, and he entered Sunday's game with a questionable tag. The 21-year-old should remain in starting fantasy lineups in a plus matchup against a Jets team that lost two of their best playmakers at the trade deadline on Tuesday in defensive lineman Quinnen Williams and cornerback Sauce Gardner. Fannin comes into Sunday's tilt with team highs in catches (38), receiving yards (352), and targets (51) while also scoring twice to begin his NFL career. His fantasy ceiling is a bit capped with David Njoku also being involved, but at the very least, Fannin should be considered a low-end TE2 for fantasy managers now that he's officially playing.

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Minnesota Vikings RB Aaron Jones (shoulder) is active for Week 10's game versus the Baltimore Ravens.

Fantasy Spin: Jones had been listed as questionable on the injury report after participating on a limited basis in two of Minnesota's three practice sessions during the week. He should see the bulk of the carries for the Vikings this afternoon and can be deployed as an RB2 or flex option in fantasy league lineups.

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The Miami Dolphins have declared QB Quinn Ewers, CB Rasul Douglas, LB Andre Carter II, WR Dee Eskridge, S Ashtyn Davis, LB Chop Robinson and TE Julian Hill inactive for Week 10.

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New Orleans Saints running back Alvin Kamara (ankle) is officially active for Sunday's Week 10 contest against the Carolina Panthers. He had been listed as questionable after practicing in a limited capacity. It's been a rough stretch of games for Kamara, who has just 12 carries over his last two games and is averaging just 2.7 yards per carry since Week 5. His usage and productivity in the receiving game have dwindled, too. However, he has a chance to bounce back in a favorable matchup against the Panthers. Fantasy managers should give him one more chance to produce as a low-end RB2 this week.

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As expected, New York Jets wide receiver Garrett Wilson (knee) is active for the Week 10 game on Sunday against the Cleveland Browns. After missing a couple of games due to a hyperextended knee, Wilson is ready to go coming out of the team's Week 9 bye. The 25-year-old will immediately return to being the team's top wideout, and he shouldn't face any restrictions this weekend. The drawback for fantasy managers is that the Jets have had one of the worst passing attacks in the league this year, and Wilson will have a bad matchup against Cleveland's defense. Targets shouldn't be an issue for Wilson, but efficiency against the Browns could be. Wilson comes into Week 10 action with 36 receptions on the year for 395 yards and four touchdowns in six games as quarterback Justin Fields' top target. Despite the tough matchup, fantasy managers should get him back into their lineups.

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Carolina Panthers wide receiver Tetairoa McMillan (hamstring) is officially active for Sunday's Week 10 contest against the New Orleans Saints. He had been listed as questionable after popping up on the injury report as a limited participant this past Friday. The rookie has impressed through nine games, ranking as the overall WR21 in PPR leagues with 41 catches, 558 yards, and a pair of touchdowns. A matchup against the Saints should lead to plenty of scoring opportunities, which bodes well for McMillan and his Panthers teammates.

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There is a possibility that Arizona Cardinals QB Kyler Murray (foot) may have played his final down with the team, according to NFL Network's Ian Rapoport. He is currently on the Reserve/Injured list due to a mid-foot sprain but recently lost his starting job to veteran QB Jacoby Brissett and may not get it back even after he is completely healthy. The Cardinals could explore trading or releasing Murray during the offseason, with a trade being preferable from the team's standpoint because it would be less expensive for them. From Murray's point of view, a release would be better because his deal would be offset, allowing him to sign with a potential playoff contender in need of a quarterback for the league minimum.

Fantasy Spin: Murray will have earned $140.5 million by the end of this season on a five-year, $230.5 million deal that he signed in July 2022, with an additional $36.835 million in fully guaranteed money forthcoming in 2026. However, if Murray remains on the Cardinals' roster on the fifth day of the new league year in March 2026, Arizona would owe him an extra $19.5 million in fully guaranteed money for 2027. Regardless of how this situation ends up, the Cardinals are on the hook for a lot of money. For now, Brissett should only be viewed as a starting option in two-quarterback fantasy leagues.

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New England Patriots running back TreVeyon Henderson and wide receiver Kyle Williams are expected to be more involved during Sunday's Week 10 game against the Tampa Bay Buccaneers, according to Tracy Wolfson of CBS. Both rookies will see increased workloads due to their teammates' injuries. Henderson is stepping into the lead-back role for the second consecutive week with Rhamondre Stevenson (toe) sidelined. The Ohio State product handled a 75 percent snap share last week, getting involved on the ground and through the air. Meanwhile, Williams should earn more snaps and targets with Kayshon Boutte (hamstring) sidelined. Williams logged a season-high (and, thus, career-high) snap share last week after Boutte went down. He failed to catch a pass in that victory, but he should have more opportunities with at least a couple of targets headed his way this Sunday. Henderson is startable as an RB2 in fantasy football, while Williams is more of a speculative stash.

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The Indianapolis Colts believe they have found a franchise quarterback in Daniel Jones, and they plan to offer him a long-term extension this upcoming offseason, according to Ian Rapoport of NFL Network. Rapoport theorized that Jones could fetch somewhere around three years and $100 million, similar to what Baker Mayfield and Sam Darnold have been paid previously. He also reported that the Colts' confidence in Jones is the main reason why they felt comfortable trading two first-round picks for cornerback Sauce Gardner. Normally, quarterback-needy teams hold onto their first-round picks. Indianapolis' willingness to move two premium selections indicates that the organization believes it has the quarterback of its future and is ready to win now.

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When the Dallas Cowboys and Green Bay Packers agreed to the blockbuster Micah Parsons trade this past summer, the Cowboys added a clause that essentially prevents the Packers from trading Parsons to the Philadelphia Eagles or any NFC East team. According to ESPN's Adam Schefter, if the Packers trade Parsons to the Eagles in 2025 or 2026, the Packers would owe the Cowboys a first-round pick. The two teams applied the same condition to Kenny Clark, who was traded to Dallas as part of the deal and must stay out of the NFC North for the next two seasons. The clause was added due to Parsons' interest in returning to Pennsylvania to play for the Eagles. This specific trade condition initially flew under the radar, but opposing teams started to take notice when exploring the NFL's internal draft pick database ahead of the trade deadline. When the Cowboys traded multiple draft picks for Quinnen Williams at the deadline, they were prohibited from including their 2028 first-round pick in trade talks, as Dallas has to keep that selection in case they end up trading Clark. Similarly, the Packers would not have been allowed to include their 2028 first-round pick in trade talks.

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