Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Cardinals | at |  | Cubs | 12:05pm CT | Mikolas R (4-6) | Taillon R (3-2) | 12:05pm |
 | Phillies | at |  | Orioles | 12:35pm CT | Wheeler R (8-3) | Burnes R (7-2) | 12:35pm |
 | Marlins | at |  | Nationals | 12:35pm CT | Luzardo L (3-5) | Parker (4-3) | 12:35pm |
 | Rays | at |  | Braves | 12:35pm CT | Eflin R (3-4) | Waldrep R (0-1) | 12:35pm |
 | Guardians | at |  | Blue Jays | 12:37pm CT | Lively R (6-2) | Berrios R (5-5) | 12:37pm |
 | Padres | at |  | Mets | 12:40pm CT | Cease R (6-5) | Megill R (1-3) | 12:40pm |
 | Athletics | at |  | Twins | 1:10pm CT | Sears L (4-5) | Ober R (5-4) | 1:10pm |
 | Tigers | at |  | Astros | 1:10pm CT | Maeda R (2-2) | Arrighetti R (3-6) | 1:10pm |
 | Reds | at |  | Brewers | 1:10pm CT | Montas R (3-5) | Rea R (5-2) | 1:10pm |
 | Pirates | at |  | Rockies | 2:10pm CT | Skenes R (3-0) | Hudson R (2-8) | 2:10pm |
 | Angels | at |  | Giants | 3:05pm CT | Suarez L (1-1) | Harrison L (4-3) | 3:05pm |
 | Royals | at |  | Dodgers | 3:10pm CT | Singer R (4-3) | Glasnow R (6-5) | 3:10pm |
 | Rangers | at |  | Mariners | 3:10pm CT | Dunning R (4-5) | Gilbert R (3-4) | 3:10pm |
 | White Sox | at |  | Diamondbacks | 3:10pm CT | Thorpe R (0-0) | Montgomery L (4-4) | 3:10pm |
 | Yankees | at |  | Red Sox | 6:10pm CT | Stroman R (6-2) | Crawford R (2-6) | 6:10pm |
| Athletics | at | | Twins | 6:40pm CT | Estes R (2-2) | Paddack R (5-3) | 6:40pm |
