Taylor Ward delivered a tiebreaking single in the top of the 10th inning as the Los Angeles Angels notched a 3-2 victory over the host Los Angeles Dodgers on Friday in the opener of a two-game set.

The Dodgers' Shohei Ohtani hit a massive two-run homer and reached base four times in his first game against his former team, but his 455-foot blast accounted for all of his team's runs. Ohtani had two of the Dodgers' five hits. Ward had two of his team's four hits as the Angels snapped a 10-game losing streak against the Dodgers.

Jo Adell was the runner on second to start the Angels' 10th, and he was sacrificed to third. Evan Phillips replaced Anthony Banda (1-1) and retired one hitter before Ward came up with two outs and ripped a single to the left of Dodgers third baseman Enrique Hernandez and into left field.

In the bottom of the 10th, pinch runner Cavan Biggio was on second and advanced to third on a groundout. Carlos Estevez then struck out Hernandez and Gavin Lux to end it for his 14th save of the season. Angels reliever Luis Garcia (2-0) allowed one hit in two innings of scoreless ball.

Astros 14, Orioles 11

Jake Meyers clubbed a go-ahead, three-run home run in the fifth inning before Joey Loperfido recorded a pair of doubles in a nine-run sixth as Houston outlasted visiting Baltimore.

Loperfido and Jose Altuve each recorded three hits and two RBIs for Houston, which won its third game in a row. Reliever Shawn Dubin (1-1) earned his first major league win by pitching 2 1/3 innings, and Bryan Abreu earned his first save.

Gunnar Henderson homered twice for the Orioles, who also got long balls from Anthony Santander and Jorge Mateo. Adley Rutschman went 5-for-5. Orioles starter Grayson Rodriguez (8-3) allowed seven runs on nine hits over five-plus innings.

Mets 11, Cubs 1

J.D. Martinez hit a three-run homer in the first inning to power another outburst by red-hot New York, which cruised past host Chicago in the opener of a three-game series.

Jose Iglesias tied a career high with four hits and added three RBIs for the Mets, who have won 14 of 19, a span in which they have scored at least 10 runs in a game five times. New York reached double figures just once in its first 55 games.

Shota Imanaga (7-2) yielded 10 runs on 11 hits in three-plus innings for the Cubs, who fell to 9-18 since May 22.

Rays 10, Pirates 3

Josh Lowe hit two home runs while going 3-for-5 with four RBIs to help visiting Tampa Bay defeat Pittsburgh.

Colin Poche (1-1) replaced starter Ryan Pepiot in the fourth and tossed a perfect 1 2/3 innings for the Rays, who totaled 17 hits and won for the fourth time in five games.

The Pirates' Bryan Reynolds homered to extend his major-league-leading hitting streak to a career-high 18 games. Pittsburgh starter Carmen Mlodzinski (1-3) allowed one run on four hits in 1 2/3 innings.

Diamondbacks 5, Phillies 4

Gabriel Moreno belted a two-run homer and Joc Pederson and Lourdes Gurriel Jr. also went deep to fuel visiting Arizona past Philadelphia.

Each of the three had two hits and Geraldo Perdomo added an RBI single to send the Diamondbacks to their eighth win in 11 games. Arizona (38-38) reached the .500 mark for the first time since it was 9-9 on April 16.

Trea Turner launched a two-run homer and added an RBI single for the Phillies, who have lost six of their past nine games.

Braves 8, Yankees 1

Ozzie Albies and Austin Riley homered in the first inning and Chris Sale pitched five solid innings while combining with four relievers on a three-hitter as visiting Atlanta rolled past slumping New York.

Albies hit a two-run homer off a Carlos Rodon fastball on the game's second pitch and Riley hit a solo shot as the Braves jumped out to a 3-0 lead.

The Yankees lost their third straight and also fell to 2-6 in their past eight games. New York has allowed 32 runs in its past three games.

Guardians 7, Blue Jays 1

Carlos Carrasco allowed one run and struck out a season-high seven over six innings and Cleveland exploded for seven runs in the second inning while rolling over visiting Toronto.

Josh Naylor had two hits and two RBIs during the big inning. Carrasco (3-6) yielded only Vladimir Gurrero Jr.'s fourth-inning homer. He gave up four hits and no walks.

Returning from the injured list, Toronto's Yariel Rodriguez (0-2) wound up allowing five runs -- four earned -- in 1 1/3 innings.

Reds 5, Red Sox 2

Jeimer Candelario hit two solo home runs to propel Cincinnati over visiting Boston.

Candelario has a team-high 14 home runs this season and has hit eight homers in June. It was his second multi-homer game of the month. Reds starter Andrew Abbott (6-6) struck out 10 while throwing 5 2/3 innings of two-run ball, and Alexis Diaz handled the ninth for his 17th save.

Connor Wong and Jarren Duran hit solo home runs for the Red Sox. Wong and Duran each had two hits in the loss, and each owns an 11-game hitting streak. Kutter Crawford (3-7) permitted five runs (three earned) in 6 1/3 innings.

Tigers 2, White Sox 1

Carson Kelly hit a two-run homer and host Detroit snapped a four-game losing streak by edging Chicago.

Tigers starter Jack Flaherty (5-4) gave up one run and five hits while striking out eight in 5 2/3 innings. Beau Brieske pitched two innings, and Jason Foley got the last four outs for his 13th save.

Tommy Pham homered for the White Sox, who have lost three straight. Erick Fedde (5-2) gave up two runs and five hits in seven innings. He retired the last 14 batters he faced.

Rangers 6, Royals 2

Marcus Semien drove in three runs with a bases-loaded double to highlight a five-run sixth inning, leading Texas over Kansas City in Arlington, Texas.

Nathaniel Lowe had three hits, including a double, and a run, Wyatt Langford went 2-for-4 with a double and two RBIs and Jonah Heim walked three times and also had an RBI and a run as Texas took the opener of a three-game series for its second consecutive win.

Kyle Isbel homered and MJ Melendez doubled and scored a run for the Royals, who lost for the fourth time in five games. John Schreiber (3-2) allowed three runs on three hits in one-third of an inning.

Nationals 11, Rockies 5

Drew Millas homered and finished with three hits, Luis Garcia Jr. also went deep, and Washington beat Colorado in Denver.

Lane Thomas had three hits, four RBIs and finished a home run shy of hitting for the cycle while Jacob Young and CJ Abrams also had three hits apiece for Washington. Every batter in the lineup reached base for the Nationals, who had a season-high 19 hits.

Ezequiel Tovar had three hits, including a homer, Nolan Jones also went deep, and Hunter Goodman hit a two-run shot for the Rockies.

A's 6, Twins 5

Shea Langeliers hit a go-ahead home run in the eighth inning, Oakland closer Mason Miller pitched a 1-2-3 ninth and the Athletics edged visiting Minnesota.

Langeliers and Tyler Soderstrom each had two hits and three RBIs for the A's, who were swept in a four-game series in Minnesota last week. Sean Newcomb (1-0) got the win over Jhoan Duran (3-3), and Miller logged his 14th save.

Willi Castro finished with a homer, a double, three RBIs and two runs as the Twins lost their third straight. Royce Lewis hit his 10th homer in 16 games this season.

Marlins 3, Mariners 2 (10 innings)

Tim Anderson lined a walk-off single in the 10th inning as host Miami defeated Seattle for its third straight walk-off win, something the club had not done since 1999.

On a first-pitch fastball by reliever Austin Voth (2-1), Anderson singled to left fielder Dominic Canzone, who made a strong throw home. But catcher Cal Raleigh couldn't come up with a short hop, and automatic runner Jake Burger came in to score.

Miami's bullpen provided 3 2/3 scoreless innings. Anthony Bender (2-2) was part of that effort as he earned the win with one scoreless frame.

Padres 9, Brewers 5

Jake Cronenworth's first career five-hit game included a tiebreaking single in the seventh inning, helping San Diego rally from a three-run deficit to top visiting Milwaukee.

The victory might prove costly for the Padres, though. Fernando Tatis Jr. exited two innings after he was hit in the left arm by a third-inning pitch. The team announced he sustained a left triceps contusion. Jurickson Profar came out in the seventh inning because of an apparent leg injury.

Brice Turang, Christian Yelich and Willy Adames each had two hits for the Brewers, who have lost two in a row. The Padres have won three straight.