New Orleans Saints (2-9) at Miami Dolphins (4-7)

Sunday, 1 p.m. ET

FanDuel odds: Dolphins -5.5, Total 42.5

Series Rewind: Miami has only one victory in the past four meetings, a 20-3 victory in 2021 with wide receiver Jaylen Waddle snagging 10 passes for 92 yards. His 1-yard TD catch in the third quarter put Miami in front 17-3.

Self-described delusional pass rusher Bradley Chubb reminded naysayers the Dolphins are very much in the playoff picture if they refuse to lose the rest of the regular season. Implausible as it might seem, the Dolphins draw a home date with two-win New Orleans to close out November and keep hope alive for a late-season miracle. The Miami Dolphins were one of the most disappointing teams in the NFL when they lost seven of their first nine games. But then they routed the Buffalo Bills 30-13 on Nov. 9, beat the Washington Commanders 16-13 in overtime in Madrid and return to action Sunday after a bye week. What running back De'Von Achane has done has been important, as well as coach Mike McDaniel's points of appreciation for Tua Tagovailoa's recent rise. Achane, who had 120 rushing yards and 45 receiving yards against the Commanders, is averaging 115.5 yards from scrimmage. New Orleans has a similar dual-threat running back in Alvin Kamara, but he's fighting multiple injuries, a drain for an offense that didn't score a touchdown against the Falcons and hasn't produced as many as 20 points in any of the past six games. The Saints are last in the NFL in red-zone touchdown percentage. They made three trips into the red zone against Atlanta and came away with a total of three points.

Houston Texans (6-5) at Indianapolis Colts (8-3)

Sunday, 1 p.m. ET

FanDuel odds: Colts -3.5, Total 44.5

Series Rewind: Texans coach DeMeco Ryans is 3-1 against the Colts, who haven't won the division title since 2014.

Much more than legitimacy as an AFC contender is at stake for Indianapolis in the Colts' first home game since Oct. 26. The Texans have won three in a row to climb another rung closer in the South standings and now the two-time defending division champs are closer to being whole on offense. C.J. Stroud sat out the past three games in concussion protocol while Houston leaned on a defensive front with a dynamite pair of edge rushers crashing opposing quarterbacks. Danielle Hunter has 11 sacks and Will Anderson Jr. is at 10 1/2 this season. Stroud was a full practice participant on Wednesday and Thursday, signaling a potential return this week. Almost any outcome except the Tennessee Titans rising to the top remains possible in the division with Jacksonville (7-4) separating the Colts and third-place Texans. Indianapolis has lost two of three and visits the Jaguars next week. The bad news for Indy is QB Daniel Jones (fractured fibula) is far from healthy and has been turnover-prone this month. Anthony Richardson, Jones' backup, has Indy's only win over Houston the past two seasons and was drafted by the Colts after the Texans selected Stroud and Anderson with consecutive picks in the 2023 draft. But the Colts can stem the Texans' pass rush by feeding NFL rushing leader Jonathan Taylor, who has 1,067 yards from scrimmage (133.4 per game) and 10 TDs (nine rushing) in eight career games vs. Houston.

San Francisco 49ers (8-4) at Cleveland Browns (3-8)

Sunday, 1 p.m. ET

FanDuel odds: 49ers -5, Total 36.5

Series Rewind: The Browns have won five of the past seven meetings, including a 19-17 home win in 2023 when San Francisco's Brock Purdy was just 12-of-27 passing.

The 49ers have won their two games since Purdy (toe) returned, but he has been far from perfect. Purdy threw three interceptions in Monday's 20-9 victory over the Carolina Panthers and averaged just 6.0 yards per passing attempt. For the season, Purdy has been picked off seven times in four games. Star running back Christian McCaffrey has 12 touchdowns (seven rushing, five receiving) and leads the NFL with 81 catches. San Francisco's points allowed versus Carolina was a season low for a defense that earlier sustained season-ending injuries to star linebacker Fred Warner and former NFL Defensive Player of the Year Nick Bosa. Now the 49ers will look to confuse Cleveland's Shedeur Sanders, who will be making his second career start. Sanders guided the Browns to a 24-10 road win over the Las Vegas Raiders in start No. 1, passing for 209 yards and one touchdown while being intercepted once. The Cleveland defense racked up 10 sacks, including three by Myles Garrett and 2 1/2 from Maliek Collins. Garrett has a league-leading 18 sacks - five more than any other NFL player -- and has seven sacks over the past two games. He also is taking dead aim at the single-season record of 22.5 shared by Michael Strahan (2001) and T.J. Watt (2021).

Los Angeles Rams (9-2) at Carolina Panthers (6-6)

Sunday, 1 p.m. ET

FanDuel odds: Rams -10.5, Total 45.5

Series Rewind: Los Angeles has won the past two meetings after the Panthers prevailed in six of the previous seven contests.

The Rams have won six consecutive games and own the best record in the NFC. Los Angeles allows a league-low 16.3 points per game and last week's 34-7 rout of the Tampa Bay Buccaneers marked the fifth team the Rams allowed 10 or fewer points this season. Byron Young has stood out with a career-high nine sacks and fellow linebacker Nate Landman leads the team with 98 tackles and four forced fumbles. Matthew Stafford has been superb with a league-high 30 touchdown passes - only three others have 20 or more - and just two interceptions. He's in a two-horse MVP race with New England Patriots quarterback Drake Maye. The Panthers are just a half-game behind the Tampa Bay Buccaneers in the NFC South but offensive inconsistency is a problem. Carolina has scored 30 points three times and also has scored 13 or fewer points on six occasions. Bryce Young passed for a franchise-record 448 yards against the Atlanta Falcons on Nov. 16 and has topped 200 yards just one other time this season. Cornerback Jaycee Horn has a career-high five interceptions but is dealing with a concussion and hasn't practiced yet this week. The Panthers will be without safety Tre'von Moehrig (81 tackles), who was suspended one game for unsportsmanlike conduct due to an incident in last week's loss to the 49ers.

Arizona Cardinals (6-5) at Tampa Bay Buccaneers (3-8)

Sunday, 1 p.m. ET

FanDuel odds: Buccaneers -2.5, Total 43.5

Series Rewind: The Buccaneers won each of the last two meetings by three points, including a 19-16 overtime win in overtime on Christmas Day 2022 when Tom Brady was the quarterback.

Baker Mayfield has made 45 consecutive starts since joining Tampa Bay, but that streak is in jeopardy due to his sprained left shoulder. Mayfield said it will come down to "pain tolerance" per whether he will be able to take the field. He hurt the shoulder multiple times during last week's 34-7 loss to the Los Angeles Rams. Teddy Bridgewater, who last started an NFL game in Week 17 of 2022 for the Miami Dolphins, is being prepared to start if necessary. The Buccaneers, who have lost three straight games and four of five, hope to have running back Bucky Irving (shoulder/foot) back after a seven-game absence. Arizona has lost three consecutive contests and eight of the past nine. Jacoby Brissett will be making his seventh consecutive start in place of Kyler Murray (foot). He has thrown for 769 yards on 80-for-106 passing (75.5%) over the past two games. Star tight end Trey McBride has caught five or more passes in 13 straight games, tying the club record set by Larry Fitzgerald. He also is tied for second in the NFL with 80 receptions. Wideout Marvin Harrison Jr. (appendicitis) is expected to play after missing the past two games.

Atlanta Falcons (4-7) at New York Jets (2-9)

Sunday, 1 p.m. ET

FanDuel odds: Falcons -2.5, Total 39.5

Series Rewind: The Falcons lead the all-time series 9-5 and have won the last three overall games vs. the Jets and the last three games at the Jets.

Atlanta slim playoff chances alive last week by snapping their five-game losing streak at New Orleans. They'll have another chance to do so Sunday against their second straight two-win opponent in the Jets. Kirk Cousins, making his first start of the season after Michael Penix Jr. sustained a season-ending partially torn ACL, completed 16 of 23 passes for 199 yards and two touchdowns. He was supported by a Falcons defense which had five sacks to run its season total up to 39, third-most in the league. Half of last week's sacks came from rookies James Pearce Jr. and Jalon Walker, who have combined for nine this season. Unfortunately for Cousins, it sounds like he'll be without star receiver Drake London (knee) again this week. He hasn't practiced and was labeled doubtful. New York's Tyrod Taylor will make his second straight start since Justin Fields was benched two weeks ago. He completed 17 of 28 passes for 228 yards, a touchdown and an interception in a 23-10 loss to the Ravens. In four games this season, Taylor has completed 61.9% of his passes for 601 yards, four touchdowns and four picks. The Jets currently rank last in the league in passing offense (145.7), nearly 18 yards less than any other team, and are still looking for their first 400-yard receiver this season

Jacksonville Jaguars (7-4) at Tennessee Titans (1-10)

Sunday, 1 p.m. ET

FanDuel odds: Jaguars -6.5, Total 41.5

Series Rewind: Jacksonville has won five of the last six games in this division rivalry, but Tennessee possesses a 35-26 lead in the all-time series.

Jacksonville enters this week in playoff position as the No. 6 seed and riding a two-game winning streak coming off last week's 27-24 overtime win over the Arizona Cardinals. Four of the team's final six games will be played against division opponents, starting this week with the first of two matchups against the Tennessee Titans. A big part of the Jaguars' recent success has been an uptick in pass-rush success. Coen challenged his defense, which had eight sacks through the first seven games, to make a bigger impact. The Jaguars responded with 13 sacks in four games since their bye week, including a season-high six last week. Receiver Brian Thomas Jr. (ankle) returned to full practice participation yesterday and appears possible to return from his three-game absence, but defensive end Travon Walker (knee) hasn't practiced this week and may be missing his second straight game. Tennessee carries a six-game overall losing streak and a 10-game home losing streak into this week. Even with a depleted receiver room, Cam Ward completed 28 of 42 passes for 256 yards and a touchdown with a team-high 37 rushing yards and his first career rushing TD. The Titans have been putting up more of a fight recently despite the losses continuing to stack. After six of the Titans' first seven losses were by 10-plus points - including four by 18-plus points - their last three have all one-score losses.

Minnesota Vikings (4-7) at Seattle Seahawks (8-3)

Sunday, 4:05 p.m. ET

FanDuel odds: Seahawks -11.5, Total 41.5

Series Rewind: Eleven months ago Sam Darnold came up clutch for the Vikings and beat Seattle 27-24, answering a Seahawks touchdown with a 30-second TD drive by finding Justin Jefferson for a 39-yard strike that proved to be the game winner.

Wanderlust might only be the fault of the Minnesota brass this week with the Vikings headed to Seattle to see what they're missing in Darnold. The Vikings who also set free Daniel Jones into the market in March -- he's 8-3 with the Colts -- are trudging forward with the developmental plan at the position centered on J.J. McCarthy growing rapidly. But he's been hurt -- and spent the week in concussion protocol -- leaving the Vikings in an unsolicited get-to-know moment with undrafted rookie Max Brosmer. Brosmer's likely starting debut comes in a tough environment, even if Seattle has been well shy of perfect at home. Darnold's 69.5 completion percentage is top five in the league, just ahead of Jones. McCarthy is last (54.1%) among quarterbacks with multiple starts. Seattle's offense relies on Jaxon Smith-Njigba, who caught two TD passes at Tennessee last week. He leads the NFL in receiving yards with 1,313 and already has eclipsed the franchise record. With six games remaining, he could become the NFL's first 2,000-yard receiver.

Las Vegas Raiders (2-9) at Los Angeles Chargers (7-4)

Sunday, 4:25 p.m. ET

FanDuel odds: Chargers -9.5, Total 40.5

Series Rewind: The Chargers swept the season series last year for the first time since 2018. They've won three straight against the Raiders to trim their deficit in the all-time series to 69-61-2.

Los Angeles has had two weeks to dwell on its worst loss of Jim Harbaugh's tenure, a 35-6 loss at Jacksonville. It hopes to find a bit more continuity against the Raiders after Justin Herbert had a career-low 81 yards passing, was sacked twice and was checked for a concussion late in the first half in the last game. Herbert has been sacked 35 times, fourth most in the NFL. A Raiders defense which ranks 27th in the league with 20 sacks this season -- despite having a standout pass-rusher in Maxx Crosby -- may be a get-right opportunity for the Chargers. Los Angeles opened the practice window for rookie RB Omarion Hampton (ankle) this week, and he was limited Wednesday and Thursday in practice. Las Vegas has its own offensive issues, so much so that Pete Carroll fired offensive coordinator Chip Kelly last Sunday after the team scored just 10 points in its fifth straight loss against Cleveland. Its offense is third worst in the NFL with 268.9 yards per game, next to last with 79.5 yards rushing and tied for worst at 15.0 points per game. Quarterback Geno Smith has Herbert beat, having been sacked 41 times this season, including 10 last week. Crosby (knee) returned to full practice participation Thursday after he was limited Wednesday. Tight end Michael Mayer (ankle) has not practiced this week after sustaining an injury in last week's game.

New

Buffalo Bills (7-4) at Pittsburgh Steelers (6-5)

Sunday, 4:25 p.m. ET

FanDuel odds: Bills -3.5, Total 46.5

Series Rewind: After Pittsburgh dominated from 1993 through 2016 -- winning 10 of 11 meetings, including playoffs -- the Bills turned the tables during the Josh Allen era. Buffalo has won four of the past five, most recently 31-17 in the wild-card round in January 2024.

This game carries significant implications for both teams as they try to boost their AFC playoff hopes. Some players might deflect the importance of the matchup, but Josh Allen leaned in, saying his Bills are operating with an "extremely high sense of urgency" after their 23-19 loss against the Houston Texans last week. The reigning NFL MVP has completed 69.7 percent of his passes for 2,709 yards, 18 touchdowns and nine interceptions in 11 starts. He's also dealing with a right elbow injury but has been a full participant at practice. Speaking of quarterback injuries, Pittsburgh's Aaron Rodgers sat out last week's 31-28 loss to the Chicago Bears with an injury to his non-throwing wrist. He was considered a full participant in Thursday's practice. If he can't go, Mason Rudolph would draw a second straight start. Jaylen Warren leads the Steelers with 604 rushing yards, and DK Metcalf is tops in the passing game with 573 receiving yards and five touchdowns on 42 catches. The Bills have continued to operate a terrific ground game, with James Cook ranking second in the league at 1,084 rushing yards. They may also give Brandin Cooks his debut after signing the free agent receiver this week.

Denver Broncos (9-2) at Washington Commanders (3-8)

Sunday, 8:20 p.m. ET

FanDuel odds: Broncos -5.5, Total 43.5

Series Rewind: The all-time series is knotted 8-8 when counting Washington's win in Super Bowl XXII. The teams have alternated wins and losses in the past eight meetings, with the Commanders prevailing 35-33 in 2023.

The Broncos and Commanders are each coming out of their bye week but are pointed in distinctly opposite directions. Denver has won eight straight and most recently defeated division rival and AFC champion Kansas City 22-19. Washington has had the bottom fall out with six losses in a row, including 16-13 in overtime to the Miami Dolphins two weeks ago in Madrid. Broncos coach Sean Payton pointed out one of his team's few deficiencies was discipline; they've committed a league-high 93 penalties for 883 yards, and they're minus-3 in turnover ratio, with only nine takeaways. Denver's third-ranked defense has carried it while Bo Nix has been hot and cold. After Nix was held to 173 and 150 yards in low-scoring wins over Houston and Las Vegas, he amassed 295 yards in the Chiefs win. Nix might be licking his chops against a Commanders defense that ranks 31st in yards allowed and 28th in scoring. Washington quarterback Jayden Daniels (non-throwing elbow) returned to practice Wednesday, although Marcus Mariota is expected to make his sixth start Sunday. Wide receivers Terry McLaurin (quad) and Noah Brown (groin/knee) also returned Wednesday and practiced fully on Thursday. Broncos star cornerback Pat Surtain II (pectoral) was a full participant at Thursday's practice.